AFC Bioreactor Controllers
ILS offers the AFC bioreactor controllers for existing new or used reactors. Today ILS provides
controllers that work with bench-top glass reactors to stainless steel SIP/CIP reactors. ILS
systems work with jacketed reactors that require a ’water-box’ for heating/cooling or reactors
that have only a heating blanket.
ILS offers flexible solutions and can customize the controller to work with existing steel
SIP/CIP reactors. ILS can provide complete engineering services including P&ID, function
requirement, design and test, control panel design and manufacturing, and software
integration. The system can integrate a variety of gas flow controllers (GFC), scales, analog
inputs/outputs, digital or serial RS232/485, Mettler Toledo ISM probes, etc. into an OPC
compliant industrial grade system.



AFC 900 Bioreactor Controllers
The AFC 900 series bioreactor controller is a complete turn-key solution for glass bioreactors.
The system is a stand-alone controller that includes an Ethernet port for remote OPC data
communication. The base system includes variables speed and fixed peristaltic pumps, GFCs,
temperature/pH/DO control, and motor controller. Instrument ports include temperature
(PT100), pH, dissolved oxygen and foam. In addition, the system can come with
Mettler-Toledo ISM connections for pH, polarographic DO, and optical DO. The system also
supports digital serial connections (RS232/485) to scales and other devices
The AFC 900 can work with reactors from a variety of vendors including but not limited to New
Brunswick, Applikon, Sartorius, or home-built (DIY) reactors. The system supports OPC for
remote data acquisition and control from the ILS Batch Expert platform.
AFC 1000 Bioreactor Controllers
The AFC 1000 is intended for stainless SIP/CIP reactors from laboratory to pilot-scale. These
steel reactors useful lifetime is often much longer than that of its original controller. ILS offers
the AFC 1000 to control such reactors. ILS will work with end-users to develop a process and
instrumentation diagram (P&ID) of the existing system. From this diagram, a requirement,
design, and test specification are presented to the end-user for final approval. ILS will
manufacture, install, and support the final controller (control panel).
The AFC 1000 can include a variety of options including the ability to integrate numerous
analog and digital serial interface, PID control loops, sequential steps for SIP/CIP, and digital
on/off IO. The system can support the Mettler Toledo ISM Probes, OPC, multiple GFCs, scales,
etc.
ILS experience with developing and delivering such systems reduces the time and cost. Since
most SIP/CIP reactors will share the majority functionality, ILS can deliver fast and efficient
solutions.
AFC 100 Bioreactor Controllers
The AFC 100 is a value-based approach to bioreactor control that is especially suited for
processes that do not require a water-jacket and have fixed agitation RPM. The AFC 100 is
considered a remote terminal unit (RTU) for pH, temperature and dissolved oxygen. The
system supports 3 analog outputs to control variable speed pumps, agitators, gas flow
controllers (GFC) and 3 relay outputs to control fixed speed pumps, heaters, and valves. The
actual control is performed by external software such as ILS Batch Expert through a Modbus
interface.
The AFC 100 targets DIY users who wish to put together their own system including vessel,
pumps, GFC. The AFC 100 offers an affordable yet fully functional entry point. The footprint of
the AFC 100 is very small a well suited to setups where space utilization is a key factor.